BOSTON — Jaylen Brown had 25 points, including a key 3-pointer in the closing minutes, to help the Boston Celtics hold off the Toronto Raptors 112-106 on Friday night for its first win.

Boston opened its season with a loss at Philadelphia on Wednesday.

Jayson Tatum finished with 25 points and nine rebounds. Kemba Walker had 22 points, including 11 in the fourth quarter.

The Celtics shot only 38 percent, but it wasn’t for a lack of trying. They had 109 attempts in the game.

Pascal Siakam scored 33 points to lead the Raptors, who went 18 of 36 from the 3-point line. Kyle Lowry finished with 29 points, including six 3-pointers.

There were 12 ties and 19 lead changes, with neither team holding more than a seven-point lead.

Boston found its shot in the fourth quarter, outscoring Toronto 36-24.

The Celtics took a 101-100 lead on a Grant Williams layup off an assist by Walker.

Later, the Celtics were leading 107-106 when Brown hit a 3-pointer with 2:49 to play.

O.G. Anunoby was called for a charge on Walker with 1:26 left, which was challenged by the Raptors. But after a review the call was upheld.

Boston got a shot clock violation on its next trip down the floor, but Lowry turned it over on Toronto’s ensuing possession when his one-handed pass along the baseline sailed out of bounds with 45 seconds remaining.

Walker struggled from the field for the second straight game, missing his first five field-goal attempts. He finally got his first basket, dropping in a layup off a backdoor feed from rookie Grant Williams late in the quarter.

Coming off a 34-point game in Toronto’s season-opening win over New Orleans on Tuesday, Siakam also started slow. He missed his first four shots and was scoreless in the first quarter before he got a finger roll to fall just before halftime.

With Rondae Hollis-Jefferson (groin) and Patrick McCaw (sore right knee) unavailable, the Raptors played just eight players against the Pelicans.

They stuck with their same starting lineup of Lowry, Fred VanVleet, O.G. Anunoby, Siakam and Marc Gasol against the Celtics. But Coach Nick Nurse went a little deeper into his rotation with Toronto staring at its first back-to-back of the season Saturday at Chicago.

He wound up playing nine players. Stanley Johnson got the extra playing time, logging five minutes and scoring three points.

NOTES:  Daniel Theis left the game in the second quarter with a sprained left ankle, but returned in the third quarter … Enes Kanter (left knee contusion) Tacko Fall (concussion protocol) and Romeo Langford (sore right knee) were both inactive.