J.D. Martinez, right, is congratulated by Jarren Duran after hitting a three-run homer in the 10th inning Saturday against the Cleveland Indians. Tony Dejak/Associated Press

CLEVELAND — J.D. Martinez hit a three-run homer in the 10th inning off Nick Wittgren and the Boston Red Sox beat the Cleveland Indians 5-3 on Saturday night.

Martinez, who broke out of an 0-for-20 slump with three hits, drove a 2-1 pitch into the seats in right field for his 24th home run of the season. Martinez also singled in the first and sixth.

Jarren Duran began the 10th inning as the runner on second base and moved to third on Kyle Schwarber’s single to left off Wittgren (2-7).

“I told myself to relax, put the ball in the air and get the run in,” Martinez said. “I was fortunate to be able to flush it and get it out.”

The homer was the 24th of the season for Martinez.

“He’s a huge stud at the plate,” Red Sox starter Nathan Eovaldi said. “He’s been scuffling here a little, but you get him back swinging the way we know he can, like he was at the beginning of the season, we’re going to be even more deadly out there.”

Boston’s Adam Ottavino came on in the 10th with the bases loaded and one out. He struck out Austin Hedges before Óscar Mercado’s single cut the lead to two runs. Ottavino retired Andrés Giménez on a groundout for his 10th save and second of the series.

Martín Pérez started the 10th with José Ramírez at second. Pérez walked Franmil Reyes and hit Bradley Zimmer with the first pitch, then struck out Bobby Bradley.

Garrett Whitlock (6-2) pitched around a one-out single in the ninth.

Boston, which holds the AL’s second wild-card spot, used Jonathan Araúz’s three-run homer in the eighth inning to beat the Indians 4-3 on Friday.

The Indians stranded 13 runners and were 2 for 13 with runners in scoring position.

“We had our chances,” interim manager DeMarlo Hale said. “There are some things we can do better, but we have to put this behind us. That’s a good team over there.”

Eovaldi allowed two runs and struck out six, throwing 97 pitches in 5 1/3 innings. The right-hander gave up Franmil Reyes’ solo homer in the second.

Cal Quantrill allowed two runs, one earned, in seven innings. Boston had runners on second and third with one out in the seventh, but Araúz popped out and Duran flied out. Quantrill, who allowed Schwarber’s solo homer in the first, struck out six.

Schwarber homered to center with one out in the first, his 27th of the season. Martinez singled and scored when left fielder Daniel Johnson booted Xander Bogaerts’ double into the corner.

Reyes led off the second with a home run into the left-field bleachers, his 24th. Bradley tied the game with an RBI double. Bradley was activated from the 10-day injured list after struggling reliever James Karinchak was optioned to Triple-A Columbus. Bradley injured his knee Aug. 6.

Plate umpire Ron Kulpa remained in the game after being hit in the mask by Christian Vázquez’s foul tip in the seventh. Kulpa was checked by an Indians trainer and other members of the umpiring crew.

Red Sox Manager Alex Cora is keeping up on the conditions of Kiké Hernández, who has tested positive for COVID-19, and second baseman Christian Arroyo, who had close contact with Hernández.

“I’m always checking on them,” Cora said before the game. “We’ll keep hoping that everything goes well in the upcoming days.”

SORRY ABOUT THAT

Hedges accidentally hit Duran on the helmet when he threw a ball back to Quantrill in the third inning. The errant toss bounced off Duran’s helmet and rolled to the third-base line. Hedges patted Duran on the leg. No one was on base at the time.

TRAINER’S ROOM

Red Sox: Outfielder Danny Santana (strained left groin) is scheduled to play nine innings in a rehab game for Double-A Portland on Sunday.

Indians: Right-hander Aaron Civale (sprained right middle finger) could return to Cleveland’s rotation soon. He hit 92 mph while throwing 4 1/3 scoreless innings during a rehab assignment at Class A Lake County on Friday. … Right-hander Shane Bieber (strained shoulder) is scheduled for a bullpen session Aug. 31.