WASHINGTON (AP) — In a combustible blend of oil and politics, the Democratic-controlled Senate rejected legislation Tuesday night to force completion of the Keystone XL Pipeline. Republicans vowed to resurrect the controversial issue soon after taking two-house control of Congress in January.

The 59-41 Senate vote was one short of the 60 needed to clear the House-passed measure, and marked a severe blow to embattled Sen. Mary Landrieu of Louisiana. While President Barack Obama and much of her party oppose the bill, the third-term Democrat had commandeered control of the chamber’s agenda in hopes of securing approval of the project and boosting her chances in an uphill Dec. 6 runoff election.

Sen. Angus King, I-Maine, who opened the door on Monday to becoming the 60th vote, slammed it shut a few hours later.

All 45 Senate Republicans, including Sen. Susan Collins, R-Maine, supported the legislation to build the Canada-to-Texas pipeline. Only 14 of 55 Democrats and allied independents joined them, a total that didn’t budge despite an appeal by the Louisiana Democrat behind closed doors a few hours before the vote.

The vote was one of the last acts of this Senate controlled by the Democrats. It is expected to complete its work by mid-December.

But Republicans said a pipeline replay with the potential to spark a veto confrontation with Obama would be coming — and soon.

Sen. Mitch McConnell, R-Ky., and the incoming majority leader, said within minutes of the vote, “I look forward to the new Republican majority taking up and passing the Keystone jobs bill early in the new year.”

Her political career in jeopardy, Landrieu told reporters, “I’m going to fight for the people of my state until the day that I leave, and I hope that will not be soon.”

Rep. Bill Cassidy, Landrieu’s Republican opponent, said that Louisiana families “need better jobs, better wages and better benefits,” and the pipeline would provide them.

Democratic divisions were on vivid display in a bill that pitted environmentalists against energy advocates.

While Obama opposes the measure, likely 2016 presidential candidate Hillary Rodham Clinton has repeatedly refused to take a position. Most recently, her spokesman did not respond to two requests over the weekend to do so.

Among Senate Democrats, 14 had publicly announced their support for the bill in the hours before the vote, but several whom Landrieu had hoped would provide the critical 60th vote needed for passage failed to step forward. Among retiring lawmakers. Jay Rockefeller of West Virginia, Tim Johnson of South Dakota and Tom Harkin of Iowa all said in advance they would oppose the bill.

Several Democrats said the issue was discussed at some length at a weekly closed-door meeting of the party’s senators. Sen. Joe Manchin of West Virginia, a supporter of the bill, said Landrieu pointed out that “this vote is going to happen, whether it happens now or it happens in January, same outcome, so why not do it now? She brought it to a head.”

The project would move oil from Canada into the United States and eventually to the Gulf Coast. Supporters say it would create jobs and ease American dependence on Middle East oil. A government environmental impact statement also predicts that a pipeline would result in less damage to the climate than moving the same oil by rail.

Critics argue that the drilling itself is environmentally harmful, and said much of the Canadian crude would be exported with little or no impact on America’s drive for energy stability.

At the White House, press secretary Josh Earnest said the measure is something “the president doesn’t support because the president believes that this is something that should be determined through the State Department and the regular process that is in place to evaluate projects like this.”

On the home front, Landrieu’s campaign announced during the day that musician Stevie Wonder would perform at a fundraiser on her behalf.

In the Senate, she has repeatedly cast herself as an independent lawmaker willing to stand up to Democratic leaders as well as the White House.

Even strong Democratic opponents of the legislation credited Landrieu with making the effort to score a major victory for her oil-rich home state. “Let the record be clear forever that this debate would not be before this body if not for Sen. Landrieu’s insistence,” said Sen. Barbara Boxer of California.

That was as far as it went, though. Boxer strongly opposed the project in remarks on the floor.

In political terms, Republicans looked like they were in a win-win position, assured of dividing Democrats no matter the outcome, and in a position to force Obama to veto the legislation in the new year if it comes to that.

The proposed pipeline would run 1,179 miles from the Canadian tar sands to Gulf coast refineries. It has been at the center of a struggle since Calgary-based TransCanada proposed it in 2008. The most recent delay was caused by a lawsuit filed in Nebraska over its proposed route.

The delays have caused friction between the U.S. and Canada, which is interested in exporting its growing oil sands production.