Lewiston at Oxford Hills

Friday, 7 p.m.

Blue Devils boast no shortage of running backs. Vikings will need to develop one to move up in PTC this year.

Brunswick at Edward Little

Friday, 7 p.m.

Red Eddies should be vastly improved with 20 seniors. But Dragons always seem to give EL a battle.

Messalonskee at Mt. Blue

Friday, 7 p.m.

It’s the Eagles’ double-wing against the run-and-shoot, the spread, the power-I or whatever the heck Mt. Blue is running these days.

Leavitt at Hampden

Friday, 7 p.m.

Hornets open title defense with what could be one of their two toughest games. Also a battle of two top QBs: Jordan Hersom of Leavitt and Jon Haws of Hampden.

Lake Region at Mountain Valley

Friday, 7 p.m.

With Cam Kaubris (shoulder) back at QB and Taylor Bradley (transfer) returning at RB, Falcons shouldn’t miss a beat.

Sacopee Valley at Jay

Friday, 7 p.m.

Tigers’ young backs and receivers should get a chance to gain some confidence.

Boothbay at Liv. Falls

Friday, 7 p.m.

Senior-dominated line should keep the Andies in Campbell Class C hunt.

Madison at Winthrop

Friday, 7 p.m.

Winthrop coach Joel Stoneton is talking up the rebuilding Bulldogs. Everyone else in the league is raving about his Ramblers.

Fryeburg at Gray-NG

Friday, 7 p.m.

Patriots knocked on the door with a big senior class last year. At least this is a fair opening matchup for the sea of new faces.

Oak Hill at Lisbon

Saturday, 1:30 p.m.

“Crossover” clash between two schools less than 10 miles apart, both considered title contenders in Western C. Could be the game of the week.

Dirigo at Freeport

Saturday, 1:30 p.m.

Falcons might not give up 70 this year, but keeping the new-look Cougars close, much less threatening their 12-game winning streak, remains a tall order.

Cape Elizabeth at Poland

Saturday, 1:30 p.m.

Hopes are high for the Knights after 2-0 exhibition season. A visit from the reigning Western B champions could reveal a lot more.